Google Scholar Citation Report Jan, 2023: 
H-Index:  74, Total Citations: >27,000
5 papers with >1000 cits, 25 papers with >200 cits and 50 papers with >100 cits

Aoki M, Vinokur J, Motoyama K, Ishikawa R, Collazo M, Cascio D, Sawaya MR, Ito T, Bowie JU, Hemmi H. Crystal structure of mevalonate 3,5-bisphosphate decarboxylase reveals insight into the evolution of decarboxylases in the mevalonate metabolic pathways. J Biol Chem. 2022 Jul;298(7):102111

Liu H, Arbing MA, Bowie JU. Expanding the use of ethanol as a feedstock for cell-free synthetic biochemistry by implementing acetyl-CoA and ATP generating pathways. Sci Rep. 2022 May 11;12(1):7700

Corin K, Bowie JU. How physical forces drive the process of helical membrane protein folding. EMBO Rep. 2022 Feb 3;23(3):e53025

Corin K, Bowie JU. How bilayer properties influence membrane protein folding. Protein Sci. 2020 Dec;29(12):2348-2362

Liu H, Bowie JU. Cell-free synthetic biochemistry upgrading of ethanol to 1,3 butanediol. Sci Rep. 2021 May 3;11(1):9449.

Sherkhanov S, Korman TP, Chan S, Faham S, Liu H, Sawaya MR, Hsu W-T, Cheng T, Bowie JU, Isobutanol production freed from biological limits using synthetic biochemistry, Nature Comm., 10.1038/s41467-020-18124-1 (2020)

Valliere MA, Korman TP, Arbing MA, Bowie JU, A bio-inspired cell free system for cannabinoid production from inexpensive inputs, Nature Chem. Biol., 10.1038/s41589-020-0631-9 (2020)

Bowie JU, Sherkhanov S, Korman TP, Valliere MA, Opgenorth P, Liu H, Synthetic Biochemistry:  The bio-inspired cell free approach to commodity chemical production, Trends in Biotech., 38(7):766-778 (2020)

Choi HK, Min D, Kang H, Shon MJ, Rah SH, Kim HC, Jeong H, Choi HJ, Bowie JU, Yoon TY., Watching helical membrane proteins fold reveals a common N-to-C-terminal folding pathway. Science. 2019 Nov 29;366(6469):1150-1156

Valliere MA, Korman TP, Woodall NB, Khitrov GA, Taylor RE, Baker D, Bowie JU, A cell-free platform for the prenylation of natural products and application to cannabinoid production, Nature Comm., 10(1):565 (2019)

Min D, Jefferson RE, Qi Y, Wang JY, Arbing MA, Im W, Bowie JU, Unfolding of ClC chloride transporter retains memory of its evolutionary history, Nature Chem. Biol., 14, p.489–496 (2018)

Lu P, Min D, DiMaio F, Wei KY, Vahey MD, Boyken SE, Chen Z, Fallas JA, Ueda G, Sheffler W, Mulligan VK, Xu W, Bowie JU, Baker D, Accurate computational design of multipass transmembrane proteins, Science, 59:1042-1046 (2018)

Rothé B, Leettola CN, Leal-Esteban L, Cascio D, Fortier S, Isenschmid M, Bowie JU, Constam DB. Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6, Structure, 26(2):209-224 (2018)

Jefferson RE, Min D, Corin K, Wang JY, Bowie JU, Applications of single molecule methods to membrane protein folding studies, J. Mol. Biol., 430(4):424-437 (2018)

Opgenorth PH, Korman TP, Bowie JU, A molecular rheostat design that maintains ATP levels needed to drive cell-free synthetic biochemistry systems, Nature Chem. Biol., 13(9):938-942 (2017)

Korman TP, Opgenorth PH, Bowie JU, A synthetic biochemistry platform for cell free production of monoterpenes from glucose, Nature Comm., 8:15526 (2017)

Cao Z, Hutchinson JM, Sanders CR, Bowie JU, Backbone hydrogen bond strengths can vary widely in transmem-brane helices, J. Am. Chem. Soc., 139(31):10742-10749 (2017)

Woodall NB, Hadley S, Yin Y, Bowie JU, Complete Topology Inversion can be Part of Normal Membrane Protein Biogenesis, Protein Sci. 4:824-833. (2017)

Vinokur JM, Cummins MC, Korman TP and Bowie JU, An adaptation to life in acid through a novel mevalonate pathway, Sci Rep., 6:39737 (2016)

Min D, Arbing MA, Jefferson RE, Bowie JU, A simple DNA handle attachment method for single molecule mechanical manipulation experiments, Protein Sci., 25(8):1535-44 (2016)

Sherkanov S, Korman TP, Clarke SG, Bowie JU, Production of FAME biodiesel in E. coli by direct methylation with an insect enzyme, Sci. Reports, 6:24239 (2016)

Opgenorth PH, Korman TP, Bowie JU, A synthetic biochemistry module for the production of bio-based chemicals from glucose, Nature Chem. Biol., 12(6):393-5 (2016)

Cheng X, Kim JK, Kim Y, Bowie JU, Im W, Molecular dynamics simulation strategies for protein-micelle complexes, Biochim Biophys Acta, 1858(7 Pt B):1566-72 (2016)

Spielmann M, Kakar N, Tayebi N, Leettola C, Nürnberg G, Sowada N, Lupiáñez DG, Harabula I, Flöttmann R, Horn D, Chan WL, Wittler L, Yilmaz R, Altmüller J, Thiele H, van Bokhoven H, Schwartz CE, Nürnberg P, Bowie JU, Ahmad J, Kubisch C, Mundlos S, Borck G, Exome sequencing and CRISPR/Cas genome editing identify mutations of ZAK as a cause of limb defects in humans and mice, Genome Res. 26(2):183-91 (2016)

Min D, Jefferson RE, Bowie JU, Yoon T-Y, Mapping the energy landscape for second stage folding of a single membrane protein, Nature Chem. Biol., 11(12):981-7 (2015)

Woodall NB, Yin Y, Bowie JU, Dual-topology insertion of a dual-topology membrane protein, Nature Comm., 6:8099 (2015)

Nam HJ, Kim I, Bowie JU, Kim S, Metazoans evolved by taking domains from soluble proteins to expand intercellular communication network, Sci Rep. 5:9576 (2015)

Vinokur JM, Korman TP, Sawaya MR, Collazo M, Cascio D, Bowie JU, Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases, Protein Sci., Protein Sci. 24(2):212-20 (2015)

Schlebach, JP, Woodall, NB, Bowie JU and Park C, Bacteriorhodopsin folds through a poorly organized transition state, J. Am. Chem. Soc., 136(47):16574-81 (2014)

Opgenorth P, Korman TP, Bowie JU, A Synthetic Biochemistry Molecular Purge Valve Module that Maintains Oxidation/Reduction Balance, Nature Commun., 5:4113 (2014)

Leettola CN, Knight MJ, Cascio D, Hoffman S, Bowie JU, Characterization of the SAM domain of the PKD-related protein ANKS6 and its interaction with ANKS3, BMC Struct Biol. 14(1):17 (2014)

Sherkhanov S, Korman TP, Bowie JU, Improving the tolerance of Escherichia coli to medium-chain fatty acid production, Metab Eng., 25C:1-7 (2014)

Vinokur JM, Korman TP, Cao Z, Bowie JU, Evidence for a novel mevalonate pathway in archaea, Biochemistry. 53(25):4161-8 (2014)

Korman TP, Shachartsiri B, Li D, Vinokur JM, Eisenberg D, Bowie JU.  A Synthetic Biochemistry System for the in vitro Production of Isoprene from Glycolysis Intermediates, Protein Science, 23(5):576-85 (2014)

Cao, Z and Bowie JU, An Energetic Scale for Equilibrium H/D Fractionation Factors Illuminates Hydrogen Bond Free Energies in Proteins, Protein Sci., 23(5):566-75 (2014)

Chang YC, Bowie JU, Measuring membrane protein stability under native conditions, Proc Natl Acad Sci U S A.;111:219-24 (2014)

Jefferson RL, Blois T, Bowie JU,  Membrane proteins can have high kinetic stability,  J. Am. Chem. Soc., 135(40):15183-15190 (2013)

**Featured in JACS Spotlights

Korman TP, Sahachartsiri B, Charbonneau DM, Huang GL, Beauregard M, Bowie JU, Dieselzymes: development of a stable and methanol tolerant lipase for biodiesel production by directed evolution,  Biotechnol Biofuels. 6(1):70 (2013)

Bowie  JU, Structural biology. Membrane protein twists and turns, Science,  339(6118):398-9 (2013)

**Recommended by Faculty of 1000

Nam, H-J, Bowie, JU, Kim S, Rampant exchange of structure and function between membrane and water soluble proteins, PLoS Comput Biol. 9(3):e1002997 (2013)

Korman TP, Bowie JU, Crystal structure of Proteus mirabilis lipase, a novel lipase from the Proteus/psychrophilic subfamily of lipase family I.1.  PLoS One, 7(12):e52890 (2012)

Kim, J, Kim, I, Han, S-K, Bowie, JU, Kim S, The centrality-lethality rule and the evolution of gene essentiality, Sci Rep., 2:900 (2012)

Meruelo AD, Han S-K, Kim S and Bowie, Structural differences between thermophilic and mesophilic membrane proteins, Protein Science, 21(11):1746-53 (2012)

Cao Z, Bowie, JU, Shifting hydrogen bonds may produce flexible transmembrane helices, Proc Natl Acad Sci U S A, 109(21):8121-6 (2012)

**Recommended by Faculty of 1000

Schlebach JP, Cao Z, Bowie JU, Park C, Revisiting the folding kinetics of bacteriorhodopsin, Protein Sci. 21(1):97-106 (2012)

Cao Z, Schlebach J, Park C, Bowie JU. Thermodynamic stability of bacteriorhodopsin mutants measured relative to the bacterioopsin unfolded state, Biochim Biophys Acta.  1818(4):1049-54 (2012)

Stafford RL, Hinde E, Knight MJ, Pennella MA, Ear J, Digman MA, Gratton E, Bowie JU, Tandem SAM domain structure of human Caskin1: a presynaptic, self-assembling scaffold for CASK, Structure, 19(12):1826-36 (2011)

Ujwal R, Bowie JU. Crystallizing membrane proteins using lipidic bicelles, Methods., 55(4):337-41 (2011)

Knight MJ, Leettola C, Gingery M, Li H, Bowie JU. A human sterile alpha motif domain polymerizome.  Protein Sci., ;20(10):1697-706, (2011)

Stafford RL, Hinde E, Knight MJ, Pennella MA, Ear J, Digman MA, Gratton E, Bowie JU.

Structure. Tandem SAM Domain Structure of Human Caskin1: A Presynaptic, Self-Assembling Scaffold for CASK..  Structure, 19(12):1826-36 (2011)

Stafford RL, Ear J, Knight M, Bowie, JU, The Molecular Basis of the Caskin1 and Mint1 Interaction with CASK, J. Mol. Biol., 412(1):3-13 (2011)

Hong H, Bowie JU, Dramatic destabilization of transmembrane helix interactions by features of natural membrane environments, J Am Chem Soc. , 20(7):1256-64 (2011)

Meruelo AD, Samish I, Bowie JU, TMKink: A method to predict transmembrane helix kinks, Protein Sci., 20:1256-64 (2011)

Stafford RL, Tang MY, Sawaya MR, Phillips ML, Bowie JU. Crystal Structure of the Central Coiled-Coil Domain from Human Liprin-β2, Biochemistry, 50:3807-15 (2011)

Grabrucker AM, Knight MJ, Proepper C, Bockmann J, Joubert M, Rowan M, Nienhaus GU, Garner CC, Bowie JU, Kreutz MR, Gundelfinger ED, Boeckers TM. Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation, EMBO J. 2;30(3):569-81 (2011)

Bowie JU,  Membrane protein folding: how important are hydrogen bonds?, Curr Opin Struct Biol. 21(1):42-9 ( 2011)

Hong H, Blois TM, Cao Z, Bowie JU, Method to measure strong protein-protein interactions in lipid bilayers using a steric trap, Proc Natl Acad Sci U S A. 107:19802-7 (2010)

**Recommended by Faculty of 1000

Schlebach JP, Kim M-S, Joh NH, Bowie JU and Park C, Probing Membrane Protein Unfolding with Pulse Proteolysis, J. Mol. Biol., 406(4):545-51 (2010)

**Recommended by Faculty of 1000

Ryan CM, Souda P, Bassilian S, Ujwal R, Zhang J, Abramson J, Ping P, Durazo A, Bowie JU, Hasan SS, Baniulis D, Cramer WA, Faull KF, Whitelegge JP. Post-translational modifications of integral membrane proteins resolved by top-down Fourier transform mass spectrometry with collisionally activated dissociation.  Mol Cell Proteomics. 9(5):791-803.

Knight MJ, Joubert MK, Plotkowski ML, Kropat J, Gingery M, Sakane F, Merchant SS, Bowie JU, Zinc Binding Drives Sheet Formation by the SAM Domain of Diacylglycerol Kinase δ,  Biochemistry,  (2010)

Di Pietro SM, Cascio D, Feliciano D, Bowie JU, Payne GS, Regulation of clathrin adaptor function in endocytosis: novel role for the SAM domain, EMBO J., 29(6):1033-44 (2010)

Blois TM, Hong H, Kim TH and Bowie JU, Protein unfolding with a steric trap, J. Am. Chem. Soc., 131,13914-5 (2009)

**Highlighted in C&E News Article Oct. 19, 2009, 39-40

Oberai A, Joh NH, Pettit FK and Bowie JU, Structural imperatives impose diverse evolutionary constraints on helical membrane proteins, Proc. Natl. Acad. Sci., USA, 106, 17747-50 (2009)

**Highlighted in Tech. Feature, Nature 465, 823–826

**Recommended by Faculty of 1000

Joh NH, Oberai A, Yang D, Whitelegge JP, Bowie JU, Similar Energetic Contributions of Packing in the Core of Membrane and Water-Soluble Proteins, J. Am Chem. Soc., 131,10846-7 (2009)

**Highlighted in News and Views: Nature Chemical Biology 5, 614 – 615 (2009)

Blois TM, Bowie JU, G-protein-coupled receptor structures were not built in a day, Protein Sci. 18(7):1335-42 (2009).

Faham S, Ujwal R, Abramson J, Bowie JU, Practical Aspects of Membrane Protein Crystallization in Bicelles, Current Topics in Membranes, 63:109-125 (2009)

Hong H, Joh NH, Bowie JU, Tamm LK, Methods for Measuring the Thermodynamic Stability of Membrane Proteins, Methods in Enzymoloy, 55:213-36 (2009)

Massey-Gendel L, Zhao A, Boulting G, Kim H-Y, Balamotis MA, Seligman LM, Nakamoto RK and Bowie JU, “Genetic selection system for improving recombinant membrane protein expression in E. coli”, Protein Sci., 18(2):372-83 (2009)

Meruelo AD, Bowie JU, Identifying polymer-forming SAM domains, Proteins, 74(1):1-5 (2009)

Joh NH, Min A, Faham S, Whitelegge JP, Yang D, Woods VL and Bowie JU, Modest stabilization by most hydrogen bonded side chain interactions in membrane proteins, Nature, 453, 1266-70 (2008)

**Rated Must Read by Faculty of 1000

**Highlighted by News&Views in Nature Chemical Biology

Sapra KT, Balasubramanian GP, Labudde D, Bowie JU, Muller DJ, Point mutations in membrane proteins reshape energy landscape and populate different unfolding pathways, J Mol Biol., 376(4):1076-90 (2008)

Harada BT, Knight MJ, Imai S, Qiao F, Ramachander R, Sawaya MR, Gingery M, Sakane F and Bowie JU, Regulation of Enzyme Localization by Polymerization:   Polymer formation by the SAM domain of Diacylglycerol Kinase d1, Structure, 6(3):380-7 (2008)

Gorman PM, Kim S, Guo M, Melnyk RA, McLaurin J, Fraser PE, Bowie JU, Chakrabartty A, Dimerization of the transmembrane domain of amyloid precursor proteins and familial Alzheimer’s disease mutants, BMC Neurosci., 9, 17 (2008)

Plotkowski ML, Kim S, Phillips ML, Partridge AW, Deber CM, Bowie JU, The Transmembrane Domain of Myelin Protein Zero can form Dimers: Possible Implications for Myelin Construction, Biochemistry, 6:12164-73 (2007)

Nauli A, Farr S, Lee C, Kim H-Y, Faham S and Bowie JU, Polymer Driven Crystallization, Protein Sci., 16:2542-51 (2007)

Pettit FK, Bare E, Tsai A, Bowie JU, HotPatch: a statistical approach to finding biologically relevant features on protein surfaces, J. Mol. Biol., 369:863-79 (2007)

Barwe SP, Kim S, Rajasekaran SA, Bowie JU, Rajasekaran AK, Janus model of the Na,K-ATPase b-subunit transmembrane domain: distinct faces mediate alpha/beta assembly and b-b homo-oligomerization, J Mol Biol., 365:706-14 (2007)

Oberai A, Ihm Y, Kim S, Bowie JU, A limited universe of membrane protein families and folds.  Protein Sci., 5, 1723-34 (2006)

**Highlighted in Tech. Feature, Nature 465, 823–826

**Recommended by Faculty of 1000

Gundelfinger ED, Boeckers TM, Baron MK, Bowie JU, A role for zinc in postsynaptic density asSAMbly and plasticity?, Trends in Biochem. Sci., 31, 366-73 (2006)

Bowie JU, Flip-flopping membrane proteins, Nature, Struct. Mol. Biol., 13:94-96 (2006)

Baron MK, Boeckers TM, Vaida B, Faham S, Gingery M, Sawaya MR, Salyer D, Gundelfinger ED, Bowie JU, Architectural framework at the core of the post-synaptic density, Science, 311, 531-5 (2006)

**Rated Must Read by Faculty of 1000

Qiao F, Harada B, Song H, Whitelegge J, Courey AJ, Bowie JU, Mae inhibits Pointed-P2 transcriptional activity by blocking its MAPK docking site, EMBO J, 25, 70-9 (2006)

**Recommended by Faculty of 1000

Bowie JU, Solving the membrane protein folding problem, Nature, 438, 581-9 (2005)

Qiao F, Bowie JU, The many faces of SAM, SciSTKE, May 31;286 (2005)

Kim S, Jeon T-J, Oberai A, Yang D, Schmidt JJ, Bowie JU, Transmembrane glycine zippers:  physiological and pathological roles in membrane proteins, Proc. Natl. Acad. Sci. USA, 102:14278-83 (2005)

**Recommended by Faculty of 1000

Lorch M, Faham S, Kaiser C, Weber I, Mason, AJ, Bowie, JU, Glaubitz C, “How to Prepare Membrane Proteins for Solid-State NMR: A Case Study on the -Helical Integral Membrane Protein Diacylglycerol Kinase from E. coli, Chembiochem, 6, 1693-1700 (2005)

Song H, Nie M, Qiao F, Bowie JU, Courey AJ, Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response, Genes & Development, 19:1767-72 (2005)

**Recommended by Faculty of 1000

Kim CA, Sawaya MR, Cascio D, Kim W, Bowie JU, Structural organization of a SAM domain copolymer from the polycomb group proteins polyhomeotic and sex-comb-on-midleg, J. Biol. Chem., 280:27769-75 (2005)

Faham S, Boulting GL, Massey EA, Yohannan S, Yang D, Bowie JU, Crystallization of bacteriorhodopsin from bicelle formulations at room temperature, Prot. Sci. 14, 836-40 (2005)

Edwards MD, Li Y, Kim S, Miller S, Barlett W, Black S, Dennison S, Iscla I, Blount P, Bowie JU and Booth IR, Gating the MscS mechanosensitive channel: pivotal role of the glycine rich TM3 helix, Nature Struct. Mol. Biol., 12, 113-9 (2005)

Bowie JU, Border Crossing, Nature, 433, 367-9 (2005)

Partridge AW, Liu S, Kim S, Bowie JU, Ginsberg MH., Transmembrane domain helix packing stabilizes integrin alpha IIbbeta 3 in the low affinity state, J. Biol. Chem., 280:7294-300 (2005)

**Rated Must Read by Faculty of 1000

Chamberlain, AK and Bowie JU, Analysis of Side Chain Rotamers in Transmembrane Proteins, Biophys J., 87:3460-9 (2004)

Qiao F, Song H, Kim CA, Sawaya MR, Hunter JB, Rebay I, Courey AJ and Bowie JU, Derepression by depolymerization:  structural insights into the regulation of Yan by Mae, Cell, 118(2):163-73 (2004)

Kim S, Chamberlain AK, Bowie JU, A model of the closed form of the nicotinic acetylcholine receptor m2 channel pore, Biophys J. 87:792-9 (2004)

Ramachander R and Bowie JU, SAM Domains Can Utilize Similar Surfaces for the Formation of Polymers and Closed Oligomers, J Mol Biol. 342(5):1353-8 (2004)

Yohannan S, Yang D, Faham S, Whitelegge JP, Bowie JU, Proline substitutions are not easily accommodated in a membrane protein, J Mol Biol. 341(1):1-6 (2004)

Yohannan S, Faham S, Yang D, Grosfeld, D, Chamberlain AK, Bowie JU, A Cα-H···O hydrogen bond in a membrane protein is not stabilizing, J. Am. Chem. Soc., 126, 2284-5 (2004)

**Highlighted in C&E News “Concentrates”

Chamberlain AK, Lee Y, Kim S and Bowie JU, Snorkeling and anti-snorkeling preferences foster and amino acid composition bias in transmembrane helices, J. Mol. Biol., 339, 471-9 (2004)

Kim S, Chamberlain AK, Bowie JU, Membrane channel structure of Helicobactor pylori vacuolating toxin:  Role of multiple GxxxG motifs in cylindrical channels, Proc. Natl. Acad. Sci., USA, 101, 5988-91 (2004)

Bowie, JU, Membrane proteins:  A new method enters the fold, Proc. Natl. Acad. Sci., USA, 101, 126, 2284-5 (2004)

Melnyk RA, Kim S, Curran RA, Engelman DM, Bowie JU, Deber CM, The affinity of GxxxG motifs in transmembrane helix-helix interactions is modulated by long-range communication, J. Biol. Chem., 279, 16591-97 Kim S, Chamberlain AK, Bowie JU, A model of the closed from of the acetylcholine receptor M2 channel pore, Biophys. J., 87(2):792-9 (2004)

Chamberlain AC and Bowie JU, Asymmetric amino acid compositions of transmembrane b-strands, Protein Sci., 13(8):2270-4 (2004)

Yohannan S, Yang D, Faham S, Bowie JU, Evolution of transmembrane helix kinks and the structural diversity of G-protein coupled receptors, Proc. Natl. Acad. Sci. USA, 101(4): 959-963 (2004)

**Highlighted as Editor’s Choice in Science

Faham S, Yang D, Bare E, Yohannan S, Whitelegge JP, Bowie JU, Side chain contributions to membrane protein structure and stability, J. Mol. Biol., 335, 237-305 (2004)

Salwinski L, Miller CS, Smith AJ, Pettit FK, Bowie JU, Eisenberg D. The Database of Interacting Proteins: 2004 update. Nucleic Acids Res., 32, D449-51 (2004)

Kim CA and Bowie JU, SAM domains:  uniform structure, diverse function, TIBS, 28, 625-28 (2003)

Rajasekaran SA, Anilkumar G, Oshima E, Bowie JU, Liu H, Heston W, Bander NH, Rajasekaran AK, A novel cytoplasmic tail leucine based motif mediates the internalization of prostate specific membrane antigen, Mol. Biol. Cell, 14, 4835-45 (2003)

Kim S, Chamberlain AC, Bowie JU, A simple method for modeling transmembrane helix oligomers, J. Mol. Biol., 329, 831-40 (2003)

Partridge AW, Melnyk RA, Yang D, Bowie JU and Deber CM, A transmembrane mimic derived from Escherichia coli diacylglyerol kinase inhibits protein activity, J. Biol. Chem., 278, 22056-60 (2003)

Chamberlain AC, Faham S, Yohannan S, Bowie JU, Construction of helix bundle membrane proteins, Adv. Prot. Chem., 63:19-46 (2003)

Kim CA, Ramachander R, Phillips ML, Thanos CT and Bowie JU, Oligomerization dependent association of SAM domains from Byr2 and Ste4, J. Biol. Chem., 277, 39585-93 (2002)

Chamberlain AC and Bowie JU, Evaluation of CH…O bonds in native and misfolded proteins, J. Mol. Biol., 322, 497 (2002)

Tran H, Kim CA, Faham S, Bowie JU, Native interface of the SAM domain polymer of TEL, BMC Structural Biology, 2, 5 (2002).

Kim CA, Gingery M, Pilpa RM, Bowie JU, The SAM domain of Polyhomeotic forms a helical polymer, Nature Struct. Biol., 9, 453-7 (2002)

Faham S and Bowie JU, Bicelle crystallization:  A new method for crystallizing membrane proteins yields a monomeric bacteriorhodopsin structure, J. Mol. Biol., 316, 1-6 (2002)

**Recommended by Faculty of 1000

**Method used in the landmark crystallization of the first GPCR

Bowie JU,  Stabilizing membrane proteins, Curr. Opin. Struct. Biol., 11, 397-402 (2001)

Kim CA, Phillips ML, Kim W, Gingery M, Tran HH, Robinson MA, Faham S, Bowie JU, Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression, EMBO J., 20, 4173-82 (2001)

**Recommended by Faculty of 1000

Zhou Y, Lau FW, Nauli S, Yang D, Bowie JU,  Inactivation mechanism of the membrane protein diacylglycerol kinase in detergent solution, Protein Sci., 10, 378-83 (2001)

Bowie, J.U., Membrane proteins:  Are we destined to repeat history?  Curr. Opin. Struc. Biol., 10, 435-437 (2000)

Bowie, J.U., Understanding membrane protein structure by design, Nature Struc. Biol., 7, 91-4 (2000)

Nagy JK, Lau FW, Bowie JU, Sanders CR,  Mapping the oligomeric interface of diacylglycerol kinase by engineered thiol cross-linking: homologous sites in the transmembrane domain.  Biochemistry, 39, 4154-64 (2000)

Zhou, Y. and Bowie, J.U., Building a thermostable membrane protein, J. Biol. Chem., 275, 6975-6979 (2000)

Thanos, C.D., Fahem, S., Dolan, P., Goodwill, K.A., Cascio, D., Phillips, M and Bowie, J.U., Monomeric Structure of the Human EphB2 Sterile a Motif Domain, J. Biol. Chem., 274, 37301-6 (1999)

Bowie, J.U., Helix-bundle membrane protein fold templates, Protein Sci., 8, 2711-9 (1999)

Thanos, C. D. and Bowie, J.U., The p53 family members p63 and p73 are SAM domain containing proteins, Protein Sci., 8, 1708-1710 (1999)

Lau, F., Nauli, S.,  Zhou, Y. and Bowie, J.U.,  Single side-chain alterations can greatly improve the resistance of a membrane protein to irreversible inactivation,  J Mol. Biol., 290, 559-564 (1999)

Lau, F., and Bowie, J.U., The active site of diacylglycerol kinase from Escherichia coli is shared between subunits, Biochemistry, 38, 5521-5527 (1999)

Thanos, C.T., Goodwill, K.A., and Bowie, J.U., Oligomeric structure of the human EphB2 receptor SAM domain, Science,  283, 833-836 (1999)

Pettit, F. and Bowie, J.U., Protein Surface Roughness and Small Molecular Binding Sites, J. Mol. Biol., 285, 1377-1382 (1999)

Zhou, Y., Wen, J. and Bowie, J.U., A Passive Transmembrane Helix, Nature Struc. Biol.,  4, 986-90 (1997)

Bowie, J. U., Helix Packing Preferences, Nature Struc. Biol., 4, 915-17 (1997)

Bowie, J.U., Helix Packing in Membrane Proteins, J. Mol. Biol.,  272, 780-789 (1997)

Lau, F. and Bowie, J.U., A Method to Assess the Stability of a Membrane Protein, Biochemistry, 36, 5884-92 (1997)

Eisenberg, D., Lüthy, R., and Bowie, J.U., VERIFY3D:  Assessment of Protein Models with Three-Dimensional Profiles, Methods in Enzymology, 277, 396-404 (1997)

Bowie, J.U., Zhang, K., Wilmanns, M., and Eisenberg, D., 3D Profiles as a Tool For Assessing the Compatibility of an Amino Acid Sequence with a Three-Dimensional Structure,  Meth. in Enz., 266, 598-616 (1996)

Fischer, D, Rice, D, Bowie, JU and Eisenberg, D, Assigning Amino Acid Sequences to 3-Dimensional Protein Folds, FASEB J., 10, 126-136 (1996)

Thanos, C.D. and Bowie, J.U., Developmentally Expressed Myosin Heavy-Chain Kinase Possesses a Diacylglycerol Kinase Domain, Protein Sci, 5, 782-785 (1996)

Wen, J., Chen, X., Bowie, J.U.,  Exploring the Allowed Sequence Space of a Membrane Protein, Nature Struc. Biol., 3, 141-148 (1996)

Bowie, J.U., Pakula, A.P., Simon, M.,  The Three-Dimensional Structure of the Aspartate Receptor from Escherichia.coli. Acta Cryst., D51, 145-154 (1995)

Bowie, J.U., Lüthy, R. and Eisenberg, D., Three-dimensional Profiles:  Assessing the Compatibility of an Amino Acid Sequence with a Three-Dimensional Structure, In: Go M. and Schimmel, P. (eds), Tracing Biological Evolution in Protein and Gene Structures.  Elsevier Science B. V., Amsterdam, The Netherlands (1995)

Bowie, J.U. and Eisenberg, D., An Evolutionary Approach to Folding Small a-Helical Proteins that Uses Sequence Information and an Empirical Guiding Fitness Function, Proc. Natl. Acad. Sci., USA,  91, 4436-40  (1994)

Bowie, J.U. and Eisenberg, D., Inverted Structure Prediction, Curr. Opin. Struct. Biol., 3, 437-444 (1993)

Lüthy,R., Bowie, J.U., and Eisenberg, D., Assessment of Protein Models with Three-Dimensional Profiles, Nature, 356,84-85 (1992) s

Bowie, J.U., Lüthy, R, and Eisenberg, D., A Method to Identify Protein Sequences that Fold into a Known Three-Dimensional Structure, Science, 253, 164-70, (1991) citations

Brown, B., Bowie, J.U. and Sauer, R.T., The Arc Repressor is Tetrameric when bound to Operator DNA, Biochemistry, 29, 11189-95, (1990)

Bowie, J.U., Reidhaar-Olson, J.F., Lim, W.A. and Sauer, R.T.,  Deciphering the Message in Protein Sequences:  Tolerance to Amino Acid Substitutions, Science, 247, 1306-10, (1990)

Bowie, J. U. and Sauer, R.T., TraY Proteins of F and Related Episomes are Members of the Arc and Mnt Repressor Family,  J. Mol. Biol., 211, 5-6 (1990)

Bowie, J.U., Clarke, N.D., Pabo, C.O. and Sauer, R.T., Identification of Protein Folds:  Matching Hydrophobicity Patterns of Sequence Sets with Solvent Accessibility Patterns of Known Structures, Proteins, 7,257-64 (1990).

Zagorski, M.G., Bowie, J.U., Vershon, A.K., Sauer, R.T., Patel, D.J., NMR Studies of Arc Repressor Mutants:  Proton Assignments, Secondary Structure, and Long-Range Contacts for the Thermostable Proline-8 Leucine Variant of Arc,  Biochemistry, 28, 9813-25 (1990).

Bowie, J.U. and Sauer, R.T., Equilibrium Dissociation and Unfolding of the Arc Repressor Dimer,  Biochemistry, 28, 7139-7143 (1989)

Bowie, J.U. and Sauer, R.T., Identifying Determinants of  Structure and Stability for a Protein of Unknown Structure,  Proc. Natl. Acad. Sci. USA, 86, 2152-2156 (1989)

Knight K.L., Bowie J.U., Vershon A.K., Kelley R.D. and Sauer R.T.,  The Arc and Mnt repressors. A new class of sequence-specific DNA-binding protein, J. Biol. Chem., 264, 3639-42, 1989.

Bowie, J.U. and Sauer, R.T., Identification of C-Terminal Extensions that Protect Proteins from Proteolysis In VivoJ. Biol. Chem., 264, 7596-602 (1989)

Regan, L., Bowie, J.U. and Schimmel, P.R., Polypeptide Sequences Essential for RNA Recognition by an Enzyme, Science, 235, 1651-1653 (1987)

Vershon, A.K., Bowie, J.U., Karplus, T.M. and Sauer, R.T., Isolation and Analysis of Arc Repressor Mutants:  Evidence for an Unusual Mechanism of DNA Binding, Proteins, 1, 302-311 (1986)

Wright C.D., Bowie J.U. and Nelson R.D., Influence of Yeast Mannan on Release of Myeloperoxidase by Human Neutrophils: Determination of Structural Features of Mannan Required for Formation of Myeloperoxidase-Mannan-Neutrophil Complexes, Infect. Immun., 43,467-71 (1984)

Bowie J.U., Gray G.R., Synthesis and Mass Spectra of the Partially Methylated and Partially Ethylated Anhydro-D-Mannitol Acetates Derived by Reductive Cleavage of Permethylated and Perethylated Saccharomyces Cerevisiae D-Mannans, Carbohydr. Res., 129,87-97 (1984)

Bowie J.U., Trescony P.V.and Gray G.R., Analysis of Linkage Positions in Saccharomyces Cerevisiae D-Mannans by the Reductive-Cleavage Method., Carbohydr. Res., 125, 301-7 (1984)

Lundblad R.L., Nesheim M.E., Straight D.L., Sailor S., Bowie J.U., Jenzano J.W., Roberts J.D.,Mann K.G., Bovine Alpha- and Beta-Thrombin. Reduced Fibrinogen-Clotting Activity of Beta-Thrombin is not a Consequence of Reduced Affinity for Fibrinogen, J. Biol. Chem., 259, 6991-5 (1984)

Wright C.D., Bowie J.U., Gray G.R. and Nelson R.D., Candidacidal Activity of Myeloperoxidase: Mechanisms of Inhibitory Influence of Soluble Cell Wall Mannan, Infect. Immun., 42, 76-80 (1983)